Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695824 | 0.69 | SLC5A2 (0.45) | — | |
| SCHEMBL187958 | 0.68 | PYGL (0.35) | — | |
| SCHEMBL10880823 | 0.64 | IMPDH2 (0.40) | — | |
| SCHEMBL3497312 | 0.64 | PYGL (0.34) | — | |
| SCHEMBL2512298 | 0.63 | — | — | |
| SCHEMBL13063984 | 0.63 | — | — | |
| SCHEMBL782650 | 0.63 | — | — | |
| SCHEMBL10519905 | 0.63 | — | — | |
| SCHEMBL800422 | 0.63 | — | — | |
| SCHEMBL850804 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257488-A2 | Novel diaminopyrimido[4,5-d]pyrimidine glycoside and glycotide and process | WARNER-LAMBERT COMPANY (US) | 1988-03-02 | — | — | EP | disclosed |