SCHEMBL187958

SCHEMBL187958

Nc1cnc(C2O[C@H](C(O)P(=O)(O)O)[C@@H](O)[C@H]2O)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PYGL P06737 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3497312 0.80 PYGL (0.34) PYGL
SCHEMBL5544528 0.74
SCHEMBL2508912 0.74
SCHEMBL3810104 0.73 PYGL (0.39) PYGL
SCHEMBL2512298 0.72
SCHEMBL4658991 0.70
SCHEMBL8332561 0.70 PYGL (0.61) PYGL
SCHEMBL1814865 0.70 PYGL (0.61) PYGL
SCHEMBL10696530 0.68 CHRNB2 (0.30)
SCHEMBL10880823 0.66 IMPDH2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4251745-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS Acies Bio d.o.o. (SI) 2023-10-04 EP disclosed
WO-2022112509-A1 GENETICALLY ENGINEERED BACTERIUM CAPABLE OF PRODUCING CYTOKININS WITH ISOPRENOID SIDE CHAINS ACIES BIO D.O.O. (SI) 2022-06-02 WO disclosed
EP-3519582-A1 METHODS FOR DECOUPLING CELL GROWTH FROM PRODUCTION OF BIOCHEMICALS AND RECOMBINANT POLYPEPTIDES Danmarks Tekniske Universitet (DK) 2019-08-07 EP disclosed
WO-2018020012-A1 METHODS FOR DECOUPLING CELL GROWTH FROM PRODUCTION OF BIOCHEMICALS AND RECOMBINANT POLYPEPTIDES DANMARKS TEKNISKE UNIVERSITET (DK) 2018-02-01 WO disclosed
EP-2401696-A1 MAMMALIAN CELL LINE MODELS AND RELATED METHODS GT Life Sciences, Inc. (US) 2012-01-04 EP disclosed
WO-2010098865-A1 MAMMALIAN CELL LINE MODELS AND RELATED METHODS GT LIFE SCIENCES, INC. (US) 2010-09-02 WO disclosed
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 WO disclosed
EP-1490678-A4 COMPOSITIONS AND METHODS FOR MODELING BACILLUS SUBTILIS METABOLISM GENOMATICA INC (US) 2007-01-03 EP disclosed
EP-1076566-A4 ATTENUATED MUTANTS OF $i(SALMONELLA) WHICH CONSTITUTIVELY EXPRESS THE Vi ANTIGEN UNIV MARYLAND (US) 2005-01-05 EP disclosed
EP-1490678-A2 COMPOSITIONS AND METHODS FOR MODELING BACILLUS SUBTILIS METABOLISM Genomatica, Inc. (US) 2004-12-29 EP disclosed
WO-2003081207-A2 COMPOSITIONS AND METHODS FOR MODELING BACILLUS SUBTILIS METABOLISM GENOMATICA, INC. (US) 2003-10-02 WO disclosed
EP-1076566-A1 ATTENUATED MUTANTS OF $i(SALMONELLA) WHICH CONSTITUTIVELY EXPRESS THE Vi ANTIGEN THE UNIVERSITY OF MARYLAND AT BALTIMORE (US) 2001-02-21 EP disclosed
WO-1999058146-A1 ATTENUATED MUTANTS OF SALMONELLA WHICH CONSTITUTIVELY EXPRESS THE Vi ANTIGEN UNIVERSITY OF MARYLAND, BALTIMORE (US) 1999-11-18 WO disclosed
WO-1997037685-A1 GUA MUTANTS OF SHIGELLA spp. AND VACCINES CONTAINING THE SAME UNIVERSITY OF MARYLAND AT BALTIMORE (US) 1997-10-16 WO disclosed