Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693646 | 0.86 | REN (0.59) | REN | |
| SCHEMBL10696795 | 0.84 | REN (0.50) | REN | |
| SCHEMBL10521881 | 0.73 | REN (0.51) | REN | |
| SCHEMBL10908290 | 0.71 | CTSK (0.52) | RENPSMB5 | |
| SCHEMBL10522118 | 0.70 | REN (0.41) | RENPSMB5 | |
| SCHEMBL11013722 | 0.69 | REN (0.58) | REN | |
| SCHEMBL11013919 | 0.69 | REN (0.66) | REN | |
| SCHEMBL11010625 | 0.69 | REN (0.66) | REN | |
| SCHEMBL10521833 | 0.69 | REN (0.58) | REN | |
| SCHEMBL9755316 | 0.68 | REN (0.48) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262318-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-06 | — | — | EP | disclosed |