Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 18/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693646 | 0.87 | REN (0.59) | REN | |
| SCHEMBL10696575 | 0.84 | REN (0.47) | REN | |
| SCHEMBL10521881 | 0.71 | REN (0.51) | REN | |
| SCHEMBL11010625 | 0.69 | REN (0.66) | REN | |
| SCHEMBL11013919 | 0.69 | REN (0.66) | REN | |
| SCHEMBL11013722 | 0.69 | REN (0.58) | REN | |
| SCHEMBL10448496 | 0.67 | REN (0.47) | REN | |
| SCHEMBL10521833 | 0.67 | REN (0.58) | REN | |
| SCHEMBL7351443 | 0.66 | REN (0.64) | REN | |
| SCHEMBL10522554 | 0.66 | CTSD (0.37) | RENBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262318-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-06 | — | — | EP | disclosed |