Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.59 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | CTSE | P14091 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696795 | 0.87 | REN (0.50) | REN | |
| SCHEMBL10696575 | 0.86 | REN (0.47) | REN | |
| SCHEMBL10521833 | 0.80 | REN (0.58) | REN | |
| SCHEMBL29612424 | 0.77 | REN (0.59) | RENCTSD | |
| SCHEMBL10722951 | 0.75 | REN (0.53) | RENCTSD | |
| SCHEMBL10656802 | 0.74 | REN (0.57) | REN | |
| SCHEMBL10656796 | 0.74 | REN (0.57) | REN | |
| SCHEMBL10664132 | 0.74 | REN (0.62) | REN | |
| SCHEMBL10664115 | 0.74 | REN (0.62) | REN | |
| SCHEMBL11014099 | 0.74 | REN (0.58) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0262318-A2 | Renin-inhibiting amino acid derivatives | MERCK PATENT GmbH (DE) | 1988-04-06 | — | — | EP | disclosed |