Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984838 | 0.85 | MAPT (0.64) | MAPTNPSR1RAB9AHSPB1POLB | |
| SCHEMBL28165531 | 0.81 | HSPB1 (0.55) | MAPTNPSR1RAB9AHSPB1POLB | |
| SCHEMBL11072229 | 0.80 | MAPT (0.49) | MAPTNPSR1RAB9AHSPB1KMT2A | |
| SCHEMBL16479498 | 0.78 | MAPT (0.64) | MAPTNPSR1RAB9AHSPB1POLB | |
| SCHEMBL3506280 | 0.77 | MAPT (0.70) | MAPTNPSR1RAB9AHSPB1POLB | |
| SCHEMBL10697700 | 0.77 | TDP1 (0.47) | MAPTNPSR1RAB9APOLBGAA | |
| SCHEMBL11014396 | 0.75 | FAAH (0.48) | MAPTNPSR1RAB9APOLBKMT2A | |
| SCHEMBL27449389 | 0.75 | HSPB1 (0.70) | MAPTNPSR1RAB9AHSPB1POLB | |
| SCHEMBL2234015 | 0.75 | HSPB1 (0.46) | MAPTNPSR1HSPB1POLBL3MBTL1 | |
| SCHEMBL10698683 | 0.75 | TDP1 (0.44) | MAPTNPSR1RAB9APOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |