Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | XPO1 | O14980 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770762 | 0.82 | CYP1A2 (0.43) | CYP1A2TDP1POLBKDM4EALDH1A1 | |
| SCHEMBL10696259 | 0.81 | CYP1A2 (0.43) | CYP1A2TDP1POLBKDM4ELMNA | |
| SCHEMBL9534383 | 0.79 | TDP1 (0.50) | CYP1A2TDP1POLBKDM4ELMNA | |
| SCHEMBL9534833 | 0.79 | CYP1A2 (0.50) | CYP1A2TDP1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9535141 | 0.79 | CYP1A2 (0.50) | CYP1A2TDP1LMNAGAASMN1; SMN2 | |
| SCHEMBL9534033 | 0.76 | PKM (0.50) | CYP1A2TDP1KDM4ELMNAL3MBTL1 | |
| SCHEMBL9534961 | 0.76 | CYP1A2 (0.43) | CYP1A2TDP1POLBKDM4ELMNA | |
| SCHEMBL6704339 | 0.75 | KDM4E (0.54) | CYP1A2TDP1POLBKDM4ELMNA | |
| SCHEMBL9770613 | 0.74 | KDM4E (0.61) | KDM4EL3MBTL1ALDH1A1XPO1SMN1; SMN2 | |
| SCHEMBL9534657 | 0.74 | CYP1A2 (0.42) | CYP1A2TDP1KDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |