Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.75 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.75 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.75 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.75 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.53 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.53 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KDM5C | P41229 | 3/20 | 0.47 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.47 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.47 |
| ▸ | KDM6B | O15054 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL15708367 | 0.96 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL1237233 | 0.96 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL7752977 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL28729193 | 0.87 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Glycolic Acid SCHEMBL6362687 | 0.87 | — | — | |
| Succinic Acid SCHEMBL24696 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Glycolic Acid SCHEMBL1331333 | 0.87 | — | — | |
| Succinic Acid SCHEMBL21867134 | 0.87 | LMNA (1.00) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Glycolic Acid SCHEMBL811403 | 0.87 | LMNA (0.50) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL3799615 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107190251-B | A kind of gold plating liquid and preparation method thereof | 广东东硕科技有限公司 | 2018-11-16 | — | — | CN | claimed |
| EP-0253552-A2 | Preparation of unagglomerated metal oxide particles with uniform particle size | Corning Glass Works (US) | 1988-01-20 | — | — | EP | claimed |
| EP-3942007-A1 | NEW ANIONIC SURFACTANTS AND WASHING AND CLEANING AGENTS CONTAINING SAME | Henkel AG & Co. KGaA (DE) | 2022-01-26 | — | — | EP | disclosed |
| WO-2020187795-A1 | NEW ANIONIC SURFACTANTS AND WASHING AND CLEANING AGENTS CONTAINING SAME | HENKEL AG & CO. KGAA (DE) | 2020-09-24 | — | — | WO | disclosed |
| CN-107190251-B | A kind of gold plating liquid and preparation method thereof | 广东东硕科技有限公司 | 2018-11-16 | — | — | CN | disclosed |
| EP-2684559-B1 | Oil-based makeup cosmetic preparation | SHINETSU CHEMICAL CO (JP) | 2017-06-14 | — | — | EP | disclosed |
| EP-2684559-A2 | Oil-based makeup cosmetic preparation | Shin-Etsu Chemical Co., Ltd. (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20130287824-A1 | OIL-BASED MAKEUP COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-10-31 | — | — | US | disclosed |
| CN-101448927-B | Detergent product and process for its preparation and use thereof | RECKITT BENCKISER NV | 2011-04-13 | — | — | CN | disclosed |
| CN-101448927-A | Detergent product and process for its preparation and use thereof | RECKITT BENCKISER NV (NL) | 2009-06-03 | — | — | CN | disclosed |
| CN-100439483-C | Textile care composition | UNILEVER NV (NL) | 2008-12-03 | — | — | CN | disclosed |
| CN-1348489-A | Detergent composition | PROCTER & GAMBLE (US) | 2002-05-08 | — | — | CN | disclosed |
| CN-1272875-A | Detergent tablet | PROCTER & GAMBLE (US) | 2000-11-08 | — | — | CN | disclosed |
| CN-1265136-A | Cleaning composition | UNILEVER PLC (NL) | 2000-08-30 | — | — | CN | disclosed |
| CN-1265137-A | sheet-like cleaning composition | UNILEVER PLC (NL) | 2000-08-30 | — | — | CN | disclosed |
| CN-1232492-A | Detergent compositions comprising antibody controlled cellulolytic activity | PROCTER & GAMBLE (US) | 1999-10-20 | — | — | CN | disclosed |
| CN-1232491-A | Detergent compositions containing antibody-controlled amylolytic activity | PROCTER & GAMBLE (US) | 1999-10-20 | — | — | CN | disclosed |
| CN-1229429-A | Detergent compositions comprising pectin lyase | PROCTER & GAMBLE (US) | 1999-09-22 | — | — | CN | disclosed |
| CN-1037452-C | Detergent compositions containing polyhydroxy fatty acid amide surfactants and clay softening system | PROCTER & GAMBLE (US) | 1998-02-18 | — | — | CN | disclosed |
| CN-1070223-A | The purging compound that contains polyhydroxy fatty acid amide surfactant and clay softening system | PROCTER & GAMBLE (US) | 1993-03-24 | — | — | CN | disclosed |