Succinic Acid

Succinic Acid

SCHEMBL1237233

O=C(O)CCC(=O)O.OCO

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.82
EGLN1 Q9GZT9 4/20 0.82
ALKBH5 Q6P6C2 1/20 0.82
SUCNR1 Q9BXA5 1/20 0.82
SLC22A6 Q4U2R8 1/20 0.57
SLC15A2 Q16348 1/20 0.56
MAPK1 P28482 1/20 0.56
SLC13A3 Q8WWT9 1/20 0.56
OR51E2 Q9H255 1/20 0.56
CAMK2A Q9UQM7 1/20 0.56
TSHR P16473 2/20 0.53
NFKB1 P19838 1/20 0.53
PMP22 Q01453 1/20 0.53
KDM4E B2RXH2 3/20 0.50
KDM5C P41229 3/20 0.50
PHF8 Q9UPP1 3/20 0.50
KDM2A Q9Y2K7 3/20 0.50
KDM6B O15054 2/20 0.50
FFAR3 O14843 1/20 0.50
HDAC3 O15379 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL10696676 0.96 LMNA (0.75) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL15708367 0.92 LMNA (0.69) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL28729193 0.91 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL7752977 0.91 LMNA (0.82) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL4269130 0.91 LMNA (1.00) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL1331200 0.91
Succinic Acid SCHEMBL829 0.91
Succinic Acid SCHEMBL24696 0.91 LMNA (1.00) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL21867134 0.91 LMNA (1.00) LMNAEGLN1ALKBH5SUCNR1SLC22A6
Succinic Acid SCHEMBL3799615 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790137-B Polycyclic glyoxylic acid esters as photoinitiators IGM集团公司 2020-10-30 CN disclosed
CN-105358527-B Oxime ester photoinitiator 巴斯夫欧洲公司 2018-09-25 CN disclosed
CN-105358527-A Oxime ester photoinitiators BASF SE 2016-02-24 CN disclosed
EP-2467755-A1 APPARATUS AND METHOD FOR A SUB MICROSCOPIC AND OPTICALLY VARIABLE IMAGE CARRYING DEVICE BASF SE (DE) 2012-06-27 EP disclosed
EP-2303932-A1 METHOD FOR TACK FREE SURFACE PHOTOCURING OF FREE RADICALLY POLYMERIZABLE RESINS UNDER VISIBLE LIGHT PHOTOEXCITATION BASF SE (DE) 2011-04-06 EP disclosed
WO-2011020727-A1 APPARATUS AND METHOD FOR A SUB MICROSCOPIC AND OPTICALLY VARIABLE IMAGE CARRYING DEVICE BASF SE (DE) 2011-02-24 WO disclosed
EP-2212113-A1 A METHOD FOR PRODUCING AN OPTICALLY VARIABLE IMAGE CARRYING SHIM BASF SE (DE) 2010-08-04 EP disclosed
WO-2009150060-A1 METHOD FOR TACK FREE SURFACE PHOTOCURING OF FREE RADICALLY POLYMERIZABLE RESINS UNDER VISIBLE LIGHT PHOTOEXCITATION BASF SE (DE) 2009-12-17 WO disclosed
EP-2084005-A1 APPARATUS AND METHOD FOR MANUFACTURING A SECURITY PRODUCT Ciba Holding Inc. (CH) 2009-08-05 EP disclosed
WO-2009062867-A1 A METHOD FOR PRODUCING AN OPTICALLY VARIABLE IMAGE CARRYING SHIM BASF SE (CH) 2009-05-22 WO disclosed
CN-100430385-C Compound for improving storage stability of photoinitiator and application thereof CIBA SC HOLDING AG (CH) 2008-11-05 CN disclosed
WO-2008061930-A1 APPARATUS AND METHOD FOR MANUFACTURING A SECURITY PRODUCT CIBA HOLDING INC. (CH) 2008-05-29 WO disclosed
CN-1302720-C Dried meat of gastrodia tuber with low sugar JIANG SHUNKUI (CN) 2007-03-07 CN disclosed
CN-1708488-A Improvement of storage stability of photoinitiators CIBA SC HOLDING AG (CH) 2005-12-14 CN disclosed
CN-1526297-A Gastrodia tuber product and its production process 樗晨 2004-09-08 CN disclosed
CN-1524431-A Dried meat of gastrodia tuber with low sugar 樗晨 2004-09-01 CN disclosed
EP-1446410-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES Ciba SC Holding AG (CH) 2004-08-18 EP disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
WO-2003044030-A1 MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-05-30 WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed