Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.62 |
| ▸ | LTA4H | P09960 | 1/20 | 0.61 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9432281 | 0.94 | SIGMAR1 (0.71) | MAOASIGMAR1LTA4HGRIN2BSLC6A3 | |
| SCHEMBL6405835 | 0.90 | MAOA (0.73) | MAOASIGMAR1LTA4HPOLB | |
| SCHEMBL4682940 | 0.90 | SLC6A3 (0.67) | MAOASIGMAR1LTA4HSLC6A3HRH3 | |
| SCHEMBL5302082 | 0.82 | LTA4H (0.86) | SIGMAR1LTA4HGRIN2BPOLBSLC6A3 | |
| SCHEMBL83687 | 0.80 | SIGMAR1 (0.86) | SIGMAR1LTA4HGRIN2BPOLBSLC6A3 | |
| SCHEMBL20382580 | 0.79 | LTA4H (0.86) | SIGMAR1LTA4HGRIN2BPOLBSLC6A3 | |
| Hydrochloric Acid SCHEMBL7239522 | 0.79 | LTA4H (0.80) | SIGMAR1LTA4HGRIN2BPOLBSLC6A3 | |
| Hydrochloric Acid SCHEMBL8037018 | 0.79 | SIGMAR1 (0.83) | SIGMAR1LTA4HGRIN2BPOLBSLC6A3 | |
| Ammonia Solution, Strong SCHEMBL28704893 | 0.79 | SIGMAR1 (0.83) | SIGMAR1LTA4HGRIN2BPOLBSLC6A3 | |
| SCHEMBL1808667 | 0.79 | SIGMAR1 (0.57) | SIGMAR1POLBSLC6A3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |