Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978141 | 1.00 | RIPK1 (0.33) | RIPK1TDP1 | |
| SCHEMBL549324 | 0.81 | GABRP (0.34) | TDP1 | |
| SCHEMBL549323 | 0.81 | GABRP (0.34) | TDP1 | |
| SCHEMBL4346918 | 0.77 | KDM1A (0.32) | — | |
| SCHEMBL979115 | 0.77 | KDM1A (0.32) | — | |
| SCHEMBL10153650 | 0.75 | CALCRL (0.35) | — | |
| SCHEMBL12950635 | 0.75 | CALCRL (0.35) | — | |
| SCHEMBL4355728 | 0.72 | SLC6A9 (0.34) | — | |
| SCHEMBL3592708 | 0.72 | SLC6A9 (0.34) | — | |
| SCHEMBL1069083 | 0.71 | PDE4A (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271346-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2011-01-12 | — | — | EP | disclosed |
| WO-2009120652-A2 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 2009-10-01 | — | — | WO | disclosed |