Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9980534 | 0.81 | HPGD (0.53) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL14280598 | 0.73 | SMN1; SMN2 (0.63) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL14392485 | 0.70 | LMNA (0.57) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL10393407 | 0.69 | ALDH1A1 (0.82) | MAPK1L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11966912 | 0.69 | SMN1; SMN2 (0.63) | SMN1; SMN2L3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL11282594 | 0.69 | L3MBTL1 (0.70) | SMN1; SMN2L3MBTL1ALDH1A1HPGDLMNA | |
| SCHEMBL20537035 | 0.69 | ALOX12 (0.67) | SMN1; SMN2ALDH1A1KMT2AHPGDLMNA | |
| Thiophanate SCHEMBL29398343 | 0.69 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1HPGDLMNAALOX15 | |
| Thiophanate SCHEMBL20842 | 0.69 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1HPGDLMNAALOX15 | |
| SCHEMBL11835363 | 0.68 | ALDH1A1 (0.57) | SMN1; SMN2MAPK1L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251083-A2 | 4-Amino-pyrimidine derivatives | BASF Aktiengesellschaft (DE) | 1988-01-07 | — | — | EP | disclosed |