Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490128 | 0.90 | MAPT (0.61) | L3MBTL1PKMLMNAMAPTALDH1A1 | |
| SCHEMBL5563212 | 0.85 | RECQL (0.42) | L3MBTL1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL10695330 | 0.81 | MPI (0.39) | LMNAMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10707347 | 0.77 | KMT2A (0.40) | L3MBTL1PKMLMNAMAPTSMN1; SMN2 | |
| SCHEMBL2490357 | 0.77 | MAPT (0.56) | L3MBTL1PKMLMNAMAPTALDH1A1 | |
| SCHEMBL10698508 | 0.77 | MAPT (0.53) | L3MBTL1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2486706 | 0.76 | LMNA (0.42) | L3MBTL1PKMLMNAMAPTALDH1A1 | |
| SCHEMBL10693972 | 0.76 | NPC1 (0.41) | LMNAMAPTALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL10694162 | 0.76 | KMT2A (0.38) | L3MBTL1PKMLMNAMAPTSMN1; SMN2 | |
| SCHEMBL2492692 | 0.76 | MPI (0.48) | PKMLMNAMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |