Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775058 | 0.83 | TSHR (0.48) | SLC6A3TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL3956655 | 0.80 | TSHR (0.46) | SLC6A3TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL15235441 | 0.77 | KMT2A (0.41) | SLC6A3TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL6076547 | 0.75 | LMNA (0.43) | TSHRCYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL23957711 | 0.73 | TAAR1 (0.39) | CYP2D6DPP4F2TAAR1LMNA | |
| SCHEMBL24023128 | 0.72 | LMNA (0.45) | TAAR1HTR2AHRH1LMNATDP1 | |
| SCHEMBL24807334 | 0.72 | HTR2A (0.41) | SLC6A3TSHRCYP2D6CYP3A4CYP2C9 | |
| SCHEMBL776890 | 0.71 | TSHR (0.48) | SLC6A3TSHRCYP2D6CYP1A2CYP3A4 | |
| SCHEMBL11234861 | 0.70 | ALDH1A1 (0.47) | TSHRHTR2AHRH1TDP1L3MBTL1 | |
| SCHEMBL3882388 | 0.70 | SLC6A3 (0.42) | SLC6A3TSHRCYP2D6CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281036-A2 | A process for preparing a polyarylene thioether | IDEMITSU PETROCHEMICAL CO. LTD. (JP) | 1988-09-07 | — | — | EP | disclosed |