Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22519675 | 0.80 | LMNA (0.46) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL1268813 | 0.80 | LMNA (0.46) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL28106402 | 0.78 | LMNA (0.44) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL10697123 | 0.75 | SLC6A3 (0.41) | LMNAADRA2CADRA2ATSHRCYP3A4 | |
| SCHEMBL3648024 | 0.74 | ALDH1A1 (0.46) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL15235441 | 0.73 | KMT2A (0.41) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL9633963 | 0.72 | TSHR (0.46) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL1719932 | 0.70 | LMNA (0.42) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL23957711 | 0.70 | TAAR1 (0.39) | LMNAADRA2CKDM4EADRA2AHIF1A | |
| SCHEMBL9634660 | 0.70 | RIPK1 (0.44) | LMNAADRA2CKDM4EADRA2AHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216998-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | Singular Genomics Systems, Inc. (US) | 2021-10-28 | — | — | WO | disclosed |
| US-7112337-B2 | Liposome composition for delivery of nucleic acid | ALZA CORPORATION (US) | 2006-09-26 | — | — | US | disclosed |
| US-20030031704-A1 | Liposome mixture of a lipid that is neutral in charge at physiologic pH and positively charged at pH values less than physiological pH, and a lipid joined to a hydrophilic polymer by an aromatic disulfide linkage, associated with a nucleic | ALZA CORPORATION | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030031704-A1 | Liposome mixture of a lipid that is neutral in charge at physiologic pH and positively charged at pH values less than physiological pH, and a lipid joined to a hydrophilic polymer by an aromatic disulfide linkage, associated with a nucleic | DLST, LIPA, DNAJC10 | LMNA 270/4885ADRA2C 4663/4885KDM4E 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.