Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.60 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534230 | 0.97 | MEN1 (0.56) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL11726547 | 0.95 | MEN1 (0.54) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10536988 | 0.92 | MEN1 (0.51) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL2355285 | 0.85 | ESR1 (0.61) | CAMK2AALDH1A1ESR1ESR2POLB | |
| SCHEMBL9718282 | 0.83 | POLB (0.63) | MAPK1LMNAHPGDALDH1A1CYP1A2 | |
| SCHEMBL28228675 | 0.83 | MAPT (0.50) | GAAMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL1501384 | 0.83 | MAPK1 (0.50) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL1892493 | 0.82 | CTNNB1 (0.67) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL10697260 | 0.82 | CTNNB1 (0.53) | MEN1KMT2AUSP2GAAKEAP1 | |
| SCHEMBL7939201 | 0.82 | MAPT (0.64) | MEN1KMT2AUSP2GAAKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275037-A2 | Aryl ether ketones | BASF Aktiengesellschaft (DE) | 1988-07-20 | — | — | EP | disclosed |