SCHEMBL2355285

SCHEMBL2355285

O=C(O)c1ccc(O)cc1Oc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.61
ESR2 Q92731 1/20 0.61
CAMK2A Q9UQM7 1/20 0.59
TTR P02766 2/20 0.51
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
LTA4H P09960 1/20 0.48
NR1H2 P55055 1/20 0.48
BAX Q07812 1/20 0.48
CTNNB1 P35222 1/20 0.47
ALOX5 P09917 1/20 0.46
PTGS2 P35354 1/20 0.46
POLB P06746 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1892493 0.86 CTNNB1 (0.67) ESR1ESR2CAMK2ATTRALDH1A1
SCHEMBL29044584 0.86 KDM4E (0.59) ESR1ESR2CAMK2ATTRCA12
SCHEMBL10697267 0.85 MEN1 (0.60) ESR1ESR2CAMK2ATTRALDH1A1
SCHEMBL10534230 0.85 MEN1 (0.56) ESR1ESR2CAMK2ATTRALDH1A1
SCHEMBL4342420 0.84 POLB (0.58) TTRCTNNB1POLB
SCHEMBL11726547 0.83 MEN1 (0.54) ESR1ESR2CAMK2ATTRALDH1A1
SCHEMBL28412115 0.83 CTNNB1 (0.55) CAMK2ATTRALDH1A1CTNNB1POLB
SCHEMBL5974200 0.82 CAMK2A (0.49) ESR1ESR2CAMK2ATTRCA12
SCHEMBL8408145 0.82 CTNNB1 (0.61) ESR1CAMK2ATTRALDH1A1TSHR
SCHEMBL649980 0.82 TTR (0.66) TTRCTNNB1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080015-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2015-07-14 US disclosed
US-8476399-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-07-02 US disclosed
US-8252887-B2 Biocompatible polymers for medical devices RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-08-28 US disclosed
US-20120178885-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-07-12 US disclosed
EP-1746114-B1 WATER-SOLUBLE THICKENER AND COSMETIC PREPARATION CONTAINING SAME SHISEIDO CO LTD (JP) 2012-06-13 EP disclosed
US-20110237752-A1 Water Soluble Thickener And Cosmetic Preparation Containing Same SHISEIDO COMPANY, LTD (JP) 2011-09-29 US disclosed
EP-2349981-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES Rutgers, The State University of New Jersey (US) 2011-08-03 EP disclosed
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY (US) 2010-09-16 US disclosed
US-20100166686-A1 Water Soluble Thickener And Cosmetic Preparation Containing Same SHISEIDO COMPANY, LTD (JP) 2010-07-01 US disclosed
WO-2010042918-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2010-04-15 WO disclosed
US-20100047197-A1 COSMETIC FORMULATION CONTANING GLUCOSYL GLYCERIDES AND UREA BEIERSDORF AG (DE) 2010-02-25 US disclosed
US-20070231354-A1 Water-Soluble Thickener and Cosmetic Preparation Containing Same SHISEIDO COMPANY, LTD. (JP) 2007-10-04 US disclosed
EP-1746114-A1 WATER-SOLUBLE THICKENER AND COSMETIC PREPARATION CONTAINING SAME SHISEIDO COMPANY, LTD. (JP) 2007-01-24 EP disclosed
US-7087700-B2 Polymeric urethane ester tertiary amines and related personal care formulations ALZO INTERNATIONAL, INC. (US) 2006-08-08 US disclosed
US-20040086482-A1 Polymeric urethane ester tertiary amines and related personal care formulations ZOFCHAK ALBERT (US) 2004-05-06 US disclosed
EP-0556424-B1 Process for decolorizing fatty acid ester and food or cosmetic composition containing the same NESTLE SA (CH) 1998-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047197-A1 COSMETIC FORMULATION CONTANING GLUCOSYL GLYCERIDES AND UREA UGCG, UGGT1, GLA ESR1 4484/4885ESR2 4132/4885CAMK2A 4670/4885
US-20040086482-A1 Polymeric urethane ester tertiary amines and related personal care formulations BCKDK, DEK, ITK ESR1 2810/4885ESR2 3707/4885CAMK2A 4337/4885
US-20100234555-A1 BIOCOMPATIBLE POLYMERS FOR MEDICAL DEVICES ECPAS, PTGIR, RXFP1 ESR1 3907/4885ESR2 3648/4885CAMK2A 3861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.