Known targets — ChEMBL curated mechanism
823298382338688239847Rdl1Rdl2Rdl3
The experimentally established mechanism targets of Lindane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8772566 | 0.92 | FDPS (0.50) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL6052974 | 0.90 | FDPS (0.48) | FDPSSMPD1GGPS1 | |
| SCHEMBL16445975 | 0.82 | FDPS (0.46) | FDPSSMPD1GGPS1CES2 | |
| SCHEMBL3284980 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 | |
| SCHEMBL6002240 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 | |
| SCHEMBL8466412 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 | |
| SCHEMBL8422908 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 | |
| SCHEMBL658156 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 | |
| SCHEMBL7619946 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 | |
| SCHEMBL8464966 | 0.75 | SMPD1 (0.45) | FDPSSMPD1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260447-A2 | Aqueous coating composition, process for its preparation and its use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1988-03-23 | — | — | EP | disclosed |
| EP-0256540-A2 | Aqueous coating, process for its preparation and its use | Herberts Gesellschaft mit beschränkter Haftung (DE) | 1988-02-24 | — | — | EP | disclosed |