SCHEMBL8422908

SCHEMBL8422908

CCCCCCCCCCCCCCC(Cl)(CCCCCCCCCCCC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 2/20 0.45
CES2 O00748 1/20 0.45
FDPS P14324 1/20 0.45
GPR84 Q9NQS5 7/20 0.44
PPARG P37231 6/20 0.44
PPARD Q03181 6/20 0.44
PPARA Q07869 6/20 0.44
HDAC11 Q96DB2 5/20 0.44
TSHR P16473 4/20 0.44
ALDH1A1 P00352 2/20 0.44
TLR2 O60603 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
FABP4 P15090 2/20 0.44
PTPN1 P18031 2/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
MEN1 O00255 1/20 0.44
ESR1 P03372 1/20 0.44
ALOX15 P16050 1/20 0.44
PDE4A P27815 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29200163 0.96 SMPD1 (0.42) SMPD1CES2FDPSGPR84PPARG
SCHEMBL4154139 0.91 SMPD1 (0.42) SMPD1CES2FDPSGPR84PPARG
SCHEMBL8683402 0.85 FDPS (0.38) SMPD1CES2FDPSGPR84PPARG
SCHEMBL3284980 0.82 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL658156 0.82 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL7619946 0.82 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL8772566 0.82 FDPS (0.50) SMPD1CES2FDPS
SCHEMBL6002240 0.82 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL8466412 0.82 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG
SCHEMBL8464966 0.82 SMPD1 (0.45) SMPD1CES2FDPSGPR84PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765306-B1 ALKYL SULFOACETATE COMPOSITIONS AND METHODS FOR PREPARING SAME STEPAN CO (US) 1999-10-20 EP disclosed
EP-0765306-A1 ALKYL SULFOACETATE COMPOSITIONS AND METHODS FOR PREPARING SAME STEPAN COMPANY (US) 1997-04-02 EP disclosed
US-5616782-A HEATING ALKYL CHLOROESTER WITH MOLAR EXCESS OF AQUEOUS SULFITE IN PRESENCE OF SULFITATION CATALYST STEPAN COMPANY (US) 1997-04-01 US disclosed
WO-1995034532-A1 ALKYL SULFOACETATE COMPOSITIONS AND METHODS FOR PREPARING SAME STEPAN COMPANY (US) 1995-12-21 WO disclosed