Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698179 | 0.86 | TYR (0.45) | KDM4EHSD17B10PI4KBTYRABL1 | |
| SCHEMBL9835802 | 0.84 | ABL1 (0.45) | TYRABL1DHFREGFR | |
| SCHEMBL10700464 | 0.83 | PARP1 (0.43) | KDM4EHSD17B10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10700470 | 0.83 | PARP1 (0.43) | KDM4EHSD17B10ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10697725 | 0.83 | SMN1; SMN2 (0.43) | KDM4EHSD17B10ALDH1A1MAPTHPGD | |
| Hydrochloric Acid SCHEMBL10698643 | 0.82 | DHFR (0.42) | TYRDHFREGFR | |
| SCHEMBL9833430 | 0.82 | DHFR (0.42) | KDM4EHSD17B10TYRNPC1MAPK1 | |
| SCHEMBL10699088 | 0.81 | MMP2 (0.52) | KDM4EHSD17B10ALDH1A1MAPTHPGD | |
| SCHEMBL10696683 | 0.80 | ABL1 (0.55) | TYRABL1 | |
| SCHEMBL3260581 | 0.78 | MAPT (0.42) | MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |