Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ANXA2 | P07355 | 2/20 | 0.40 |
| ▸ | S100A10 | P60903 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700470 | 1.00 | PARP1 (0.43) | PARP1NPC1MEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL10704688 | 0.87 | NPC1 (0.51) | PARP1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL10697871 | 0.85 | PARP1 (0.43) | PARP1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL10697869 | 0.85 | PARP1 (0.43) | PARP1NPC1MEN1KMT2ARAB9A | |
| SCHEMBL10699088 | 0.83 | MMP2 (0.52) | NPC1MEN1KMT2ARAB9AMAPK1 | |
| SCHEMBL10697362 | 0.83 | KDM4E (0.43) | NPC1MAPK1KDM4EHSD17B10LMNA | |
| SCHEMBL10698179 | 0.81 | TYR (0.45) | NPC1MAPK1KDM4EHSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL10699712 | 0.80 | ALDH1A1 (0.43) | KDM4ELMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL9835802 | 0.79 | ABL1 (0.45) | TYR | |
| SCHEMBL10696683 | 0.77 | ABL1 (0.55) | KMT2ATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |