Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 7/20 | 0.55 |
| ▸ | WNK1 | Q9H4A3 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699088 | 0.91 | MMP2 (0.52) | ABL1KMT2ATYRROCK1MMP2 | |
| SCHEMBL9835802 | 0.84 | ABL1 (0.45) | ABL1TYR | |
| SCHEMBL10698179 | 0.84 | TYR (0.45) | ABL1TYR | |
| SCHEMBL10697362 | 0.80 | KDM4E (0.43) | ABL1TYR | |
| SCHEMBL9833430 | 0.79 | DHFR (0.42) | TYR | |
| Hydrochloric Acid SCHEMBL10698643 | 0.79 | DHFR (0.42) | TYR | |
| SCHEMBL10699109 | 0.79 | LTA4H (0.41) | — | |
| SCHEMBL10700470 | 0.77 | PARP1 (0.43) | KMT2ATYR | |
| SCHEMBL10700464 | 0.77 | PARP1 (0.43) | KMT2ATYR | |
| SCHEMBL10696821 | 0.74 | MMP2 (0.52) | ABL1KMT2ATYRROCK1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |