Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12888466 | 1.00 | CALM1 (0.59) | CALM1IGF1RALOX15HTTSMN1; SMN2 | |
| SCHEMBL2238188 | 0.89 | HTT (0.59) | CALM1HTTSMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL2942342 | 0.89 | HTT (0.59) | CALM1HTTSMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL8158210 | 0.85 | CALM1 (0.58) | CALM1IGF1RALOX15HTTSMN1; SMN2 | |
| SCHEMBL6989069 | 0.82 | CALM1 (0.56) | CALM1IGF1RALOX15HTTSMN1; SMN2 | |
| Carbon Monoxide SCHEMBL6904840 | 0.82 | ALDH1A1 (0.54) | CALM1HTTSMN1; SMN2TAAR1ALDH1A1 | |
| SCHEMBL10654362 | 0.81 | SLC6A4 (0.61) | CALM1IGF1RALOX15HTTSMN1; SMN2 | |
| SCHEMBL1238082 | 0.80 | LDHA (0.56) | CALM1ALOX5ALDH1A1F2RL1KMT2A | |
| SCHEMBL1237034 | 0.80 | LDHA (0.56) | CALM1ALOX5ALDH1A1F2RL1KMT2A | |
| SCHEMBL1236958 | 0.80 | LDHA (0.56) | CALM1ALOX5ALDH1A1F2RL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |