Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698297 | 0.91 | ALDH1A1 (0.36) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL9824039 | 0.71 | SMN1; SMN2 (0.40) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL9824718 | 0.70 | NPSR1 (0.35) | NPC1SMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL9824445 | 0.67 | NPSR1 (0.39) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL10338291 | 0.65 | NPSR1 (0.35) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL9764390 | 0.61 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2MAPTKMT2AALDH1A1 | |
| SCHEMBL16622735 | 0.60 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2TP53MAPT | |
| SCHEMBL3070093 | 0.56 | MIF (0.49) | SMN1; SMN2MIFALDH1A1LMNA | |
| SCHEMBL9463642 | 0.56 | MIF (0.49) | SMN1; SMN2MIFALDH1A1LMNA | |
| SCHEMBL2911507 | 0.55 | MMP3 (0.40) | SMN1; SMN2KMT2AALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273417-A1 | Thiadiazabicyclononane derivatives and herbicidal compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |