Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697287 | 0.89 | BCAT2 (0.31) | — | |
| SCHEMBL27692751 | 0.89 | HSD11B1 (0.37) | HSD11B1GRM4CYP3A4CYP1A2BRD9 | |
| SCHEMBL10574787 | 0.86 | ADORA3 (0.33) | HTT | |
| SCHEMBL10695876 | 0.84 | BCAT1 (0.34) | GRM4BRD9 | |
| SCHEMBL10695874 | 0.84 | BCAT1 (0.34) | GRM4BRD9 | |
| SCHEMBL7562176 | 0.82 | HSD11B1 (0.36) | HSD11B1GRM4CYP3A4LMNACYP1A2 | |
| SCHEMBL29709206 | 0.82 | HSD11B1 (0.36) | HSD11B1GRM4CYP3A4LMNACYP1A2 | |
| SCHEMBL10697188 | 0.81 | — | — | |
| SCHEMBL29452606 | 0.81 | BCAT2 (0.31) | GRM4 | |
| SCHEMBL10697818 | 0.81 | GAA (0.34) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | claimed |
| EP-0255047-A1 | 3-Aryl uraciles and their use as herbicides | CIBA-GEIGY AG (CH) | 1988-02-03 | — | — | EP | disclosed |