Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700950 | 0.90 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10698690 | 0.89 | MEN1 (0.33) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10699480 | 0.88 | KDM4E (0.34) | ALDH1A1KDM4EHPGDHSD17B10CYP3A4 | |
| SCHEMBL10699606 | 0.85 | TNKS2 (0.43) | MEN1KMT2AALDH1A1KDM4ECACNA1S | |
| SCHEMBL10697977 | 0.82 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10699909 | 0.80 | KDM4E (0.38) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10697525 | 0.80 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10698933 | 0.80 | KMT2A (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10700985 | 0.79 | KMT2A (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10699882 | 0.78 | KDM4E (0.35) | ALDH1A1KDM4EHPGDSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |