Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27614675 | 0.84 | HTT (0.35) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL776507 | 0.83 | HTT (0.39) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL775990 | 0.81 | HTT (0.41) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL7501507 | 0.80 | ALDH1A1 (0.38) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL15229567 | 0.79 | HTT (0.40) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9101581 | 0.78 | HTT (0.43) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL17417188 | 0.78 | HTT (0.54) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL600325 | 0.77 | ALDH1A1 (0.36) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL9702372 | 0.77 | ALDH1A1 (0.34) | HTTSNCAALDH1A1HSD17B10LMNA | |
| SCHEMBL29029868 | 0.76 | LMNA (0.41) | HTTSNCAALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281907-A1 | Thiazolyl ether and thioether derivatives | BAYER AG (DE) | 1988-09-14 | — | — | EP | disclosed |