SCHEMBL7501507

SCHEMBL7501507

Cc1ccc(S(=O)(=O)O)cc1C(F)C(F)F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.38
LMNA P02545 3/20 0.38
MAPT P10636 3/20 0.38
GAA P10253 2/20 0.38
HTT P42858 1/20 0.38
SNCA P37840 1/20 0.37
HSD17B10 Q99714 4/20 0.37
TDP1 Q9NUW8 2/20 0.35
TSHR P16473 3/20 0.34
NT5E P21589 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34
CASP6 P55212 2/20 0.34
TP53 P04637 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
PHLPP2 Q6ZVD8 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776507 0.86 HTT (0.39) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL15229567 0.85 HTT (0.40) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL775990 0.84 HTT (0.41) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL9101581 0.80 HTT (0.43) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL17417188 0.80 HTT (0.54) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL600325 0.80 ALDH1A1 (0.36) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL10697552 0.80 HTT (0.36) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL29029868 0.79 LMNA (0.41) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL27614675 0.78 HTT (0.35) ALDH1A1LMNAMAPTGAAHTT
SCHEMBL4026469 0.77 HTT (0.41) ALDH1A1LMNAMAPTGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118235084-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-06-21 CN disclosed
CN-118103209-A Composition for forming release layer, laminate, and method for producing laminate 日产化学株式会社 2024-05-28 CN disclosed
CN-118020019-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2024-05-10 CN disclosed
WO-2024041555-A1 METHODS OF MANUFACTURING KINASE INHIBITORS INSILICO MEDICINE IP LIMITED (CN) 2024-02-29 WO disclosed
CN-117015582-A Composition for forming release layer and release layer 日产化学株式会社 2023-11-07 CN disclosed
CN-116854630-A Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2023-10-10 CN disclosed
CN-116789871-A Composition for forming cured film, alignment material, and retardation material 日产化学株式会社 2023-09-22 CN disclosed
CN-112384834-B Cured film, alignment material, and retardation material 日产化学株式会社 2023-08-11 CN disclosed
CN-112055712-B Methods and intermediates for preparing therapeutic compounds useful in the treatment of retroviral infections 吉利德科学公司 2023-07-14 CN disclosed
CN-112041713-B Composition for forming cured film, alignment material, and retardation material 日产化学株式会社 2023-07-07 CN disclosed
CN-110291849-B Wiring forming method 日产化学株式会社 2023-06-06 CN disclosed
CN-116231075-A Electrolyte containing overcharge-preventing additive and lithium ion battery 湖北亿纬动力有限公司 2023-06-06 CN disclosed
CN-116041232-A Preparation method of trifluoroethyl thioether acaricide intermediate 浙江工业大学 2023-05-02 CN disclosed
CN-110461887-B Composition for forming cured film, alignment material, and phase difference material 日产化学株式会社 2023-04-04 CN disclosed
CN-111417400-B Fluorine substituted porphyrin compounds, pharmaceutical compositions containing the same, and methods of making and using the same 杜克大学 2022-12-02 CN disclosed
EP-1244666-A1 IMIDAZOPYRIMIDINYL AND IMIDAZOPYRIDINYL DERIVATIVES Bristol-Myers Squibb Pharma Company (US) 2002-10-02 EP disclosed
WO-2001044248-A1 IMIDAZOPYRIMIDINYL AND IMIDAZOPYRIDINYL DERIVATIVES BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2001-06-21 WO disclosed
WO-1998008813-A1 COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES ELI LILLY AND COMPANY (US) 1998-03-05 WO disclosed