SCHEMBL10697553

SCHEMBL10697553

C=CC(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.59
HPGD P15428 3/20 0.59
ALDH1A1 P00352 2/20 0.59
ALDH5A1 P51649 1/20 0.57
ABAT P80404 1/20 0.57
RAB9A P51151 6/20 0.54
NPC1 O15118 6/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
KMT2A Q03164 3/20 0.54
CASP3 P42574 1/20 0.54
CYP1B1 Q16678 1/20 0.54
SENP8 Q96LD8 1/20 0.54
SENP7 Q9BQF6 1/20 0.54
SENP6 Q9GZR1 1/20 0.54
AKT1 P31749 1/20 0.54
CRHBP P24387 1/20 0.53
CRHR2 Q13324 1/20 0.53
TLR9 Q9NR96 1/20 0.53
THRB P10828 4/20 0.52
THRA P10827 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL28260011 0.82 AKT1 (0.63) MAPTHPGDALDH1A1ALDH5A1ABAT
SCHEMBL29728324 0.82 MAPT (0.62) MAPTHPGDALDH1A1ALDH5A1ABAT
SCHEMBL300438 0.82 MAPT (0.62) MAPTHPGDALDH1A1ALDH5A1ABAT
SCHEMBL4256312 0.82 ALDH5A1 (0.80) MAPTHPGDALDH1A1ALDH5A1ABAT
SCHEMBL6263294 0.81 MAPT (0.57) MAPTHPGDALDH1A1RAB9ANPC1
SCHEMBL3046452 0.81 MAPT (0.61) MAPTHPGDALDH1A1RAB9ANPC1
Water SCHEMBL10350093 0.79 MAPT (0.59) MAPTHPGDALDH1A1RAB9ANPC1
SCHEMBL13051047 0.79 THRB (0.56) MAPTALDH1A1ALDH5A1ABATKMT2A
SCHEMBL13174425 0.79 ALDH1A1 (0.53) MAPTHPGDALDH1A1ALDH5A1ABAT
SCHEMBL1681375 0.77 ALDH1A1 (0.52) MAPTHPGDALDH1A1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105524055-A Preparation and application of fluorescent probe capable of being used for distinguishing cysteine/homocysteine and glutathione UNIV CENTRAL SOUTH 2016-04-27 CN claimed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN claimed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN claimed
CN-101802107-A Dye composition comprising at least one colourless disulfide/thiol precursor and dyeing process using said composition OREAL 2010-08-11 CN claimed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
CN-107021938-A Acetone of 3 cyanomethylene of a kind of 1 phenothiazinyl, 3 aryl 1 and preparation method thereof 陕西科技大学 2017-08-08 CN disclosed
CN-105524055-A Preparation and application of fluorescent probe capable of being used for distinguishing cysteine/homocysteine and glutathione UNIV CENTRAL SOUTH 2016-04-27 CN disclosed
CN-104140381-A Compound provided with good affinity and tangled with Abeta plaque and nerve fiber and preparation method thereof UNIV BEIJING NORMAL 2014-11-12 CN disclosed
CN-104039944-A Encapsulated benefit agent UNILEVER NV 2014-09-10 CN disclosed
CN-101223199-B Amine functionalized polymers BRIDGESTONE CORP 2014-08-13 CN disclosed
CN-102015993-B Encapsulated benefit agent UNILEVER PLC 2013-03-27 CN disclosed
CN-102015993-A Encapsulated benefit agent UNILEVER PLC 2011-04-13 CN disclosed
CN-101802107-A Dye composition comprising at least one colourless disulfide/thiol precursor and dyeing process using said composition OREAL 2010-08-11 CN disclosed
CN-101223199-A Amine functionalized polymers BRIDGESTONE CORP (JP) 2008-07-16 CN disclosed
CN-1310934-C Erythromycin 6-O-carbamoylketolide derivatives useful as antibacterial agents ORTHO MCNEIL PHARM INC (US) 2007-04-18 CN disclosed
CN-1543472-A 6-o-carbamoyl ketolide antibacterials ����-������ҩƷ��˾ 2004-11-03 CN disclosed
EP-0261602-A2 Pyridine compounds and their use BASF Aktiengesellschaft (DE) 1988-03-30 EP disclosed
EP-0073456-B1 TETRAAZAANNULENE COBALT COMPLEX COMPOUNDS AND METHOD FOR PREPARATION THEREOF Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-11-27 EP disclosed