SCHEMBL300438

SCHEMBL300438

C=CC(=O)c1ccc2cc(N(C)C)ccc2c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.62
HPGD P15428 3/20 0.62
ALDH1A1 P00352 2/20 0.62
CYP3A4 P08684 2/20 0.62
KMT2A Q03164 2/20 0.62
SMN1; SMN2 Q16637 2/20 0.62
KDM4E B2RXH2 1/20 0.62
MEN1 O00255 1/20 0.62
EGFR P00533 1/20 0.62
TP53 P04637 1/20 0.62
PKM P14618 1/20 0.62
ALOX15 P16050 1/20 0.62
ALOX12 P18054 1/20 0.62
JAK1 P23458 1/20 0.62
MAPK1 P28482 1/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
ALDH5A1 P51649 1/20 0.43
ABAT P80404 1/20 0.43
KDM2B Q8NHM5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29728324 1.00 MAPT (0.62) MAPTHPGDALDH1A1CYP3A4KMT2A
SCHEMBL10697553 0.82 MAPT (0.59) MAPTHPGDALDH1A1KMT2ASMN1; SMN2
SCHEMBL7142011 0.79 AKT1 (0.52) MAPTHPGDALDH1A1CYP3A4KMT2A
SCHEMBL30898565 0.79 MAPT (0.53) MAPTHPGDALDH1A1KMT2AKDM4E
SCHEMBL29717125 0.79 KDM4E (0.55) MAPTHPGDALDH1A1KMT2AKDM4E
SCHEMBL2701032 0.79 KDM4E (0.55) MAPTHPGDALDH1A1KMT2AKDM4E
SCHEMBL34895 0.79 MAPT (0.53) MAPTHPGDALDH1A1KMT2AKDM4E
Acrylamide SCHEMBL28131676 0.78 ALDH1A1 (0.40) MAPTHPGDALDH1A1CYP3A4KMT2A
SCHEMBL30504311 0.77 LCK (0.56) MAPTHPGDALDH1A1SMN1; SMN2KDM4E
SCHEMBL28040989 0.77 HPGD (0.48) MAPTHPGDALDH1A1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 651 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12203936-B2 Detection of glutathionylated proteins UNIVERSITEIT MAASTRICHT (NL) 2025-01-21 US claimed
CN-118126427-A Halogen-free flame-retardant rubber conveyer belt and preparation method thereof 保定顺达胶带有限公司 2024-06-04 CN claimed
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-23 US claimed
EP-3377897-B1 LACTATE BIOSENSORS AND USES THEREOF UNIV DUKE (US) 2024-05-01 EP claimed
US-11906524-B2 Urea biosensors and uses thereof DUKE UNIVERSITY (US) 2024-02-20 US claimed
US-11852637-B2 Bicarbonate biosensors, calcium biosensors, and uses thereof DUKE UNIVERSITY (US) 2023-12-26 US claimed
US-11156615-B2 Glucose biosensors and uses thereof DUKE UNIVERSITY (US) 2021-10-26 US claimed
US-20210311057-A1 DETECTION OF GLUTATHIONYLATED PROTEINS THE UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) 2021-10-07 US claimed
EP-3131655-B1 METHOD FOR THE QUANTIFICATION OF PARASITE EGGS IN FECES MEP Equine Solutions LLC (US) 2020-12-02 EP claimed
CN-106457090-B Method for quantifying parasite eggs in excrement MEP马解决方案有限责任公司 2020-09-29 CN claimed
US-20050042704-A1 Entrapped binding protein as biosensors BECTON, DICKINSON AND COMPANY 2005-02-24 US claimed
US-6855556-B2 Binding protein as biosensors BECTON, DICKINSON AND COMPANY (US) 2005-02-15 US claimed
US-20050014290-A1 Binding proteins as biosensors BECTON, DICKINSON AND COMPANY 2005-01-20 US claimed
EP-1458760-A4 ENTRAPPED BINDING PROTEINS AS BIOSENSORS BECTON DICKINSON CO (US) 2005-01-19 EP claimed
EP-1468023-A2 BINDING PROTEINS AS BIOSENSORS Becton, Dickinson and Company (US) 2004-10-20 EP claimed
EP-1458760-A1 ENTRAPPED BINDING PROTEINS AS BIOSENSORS Becton, Dickinson and Company (US) 2004-09-22 EP claimed
US-20030153026-A1 Entrapped binding protein as biosensors BECTON, DICKINSON AND COMPANY 2003-08-14 US claimed
US-20030134346-A1 Glucose biosensor; mutated binding protein with a reporter group attached that provides detectable and reversible signal change when exposed to varying glucose concentrations BECTON, DICKINSON AND COMPANY 2003-07-17 US claimed
WO-2003057851-A2 BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2003-07-17 WO claimed
WO-2003057734-A1 ENTRAPPED BINDING PROTEINS AS BIOSENSORS BECTON, DICKINSON AND COMPANY (US) 2003-07-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11906524-B2 Urea biosensors and uses thereof SLC14A1, UROD, CPS1 MAPT 1245/4885HPGD 722/4885ALDH1A1 2244/4885
US-20240168032-A1 GLUCOSE BIOSENSORS AND USES THEREOF GCK, GCKR, SLC2A4 MAPT 1875/4885HPGD 1074/4885ALDH1A1 1398/4885
US-11156615-B2 Glucose biosensors and uses thereof GCK, GCKR, SLC2A4 MAPT 1875/4885HPGD 1074/4885ALDH1A1 1398/4885
US-11852637-B2 Bicarbonate biosensors, calcium biosensors, and uses thereof CA2, CASR, CACYBP MAPT 4652/4885HPGD 2032/4885ALDH1A1 3391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.