Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757681 | 0.91 | TRPA1 (0.47) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL6569937 | 0.90 | TSHR (0.48) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL21339840 | 0.89 | HTR2A (0.54) | TSHRPOLBCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL31126411 | 0.86 | TSHR (0.50) | TSHRPOLBHPGDMEN1KMT2A | |
| SCHEMBL23531244 | 0.85 | TSHR (0.48) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL919366 | 0.85 | TSHR (0.48) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL17592400 | 0.84 | ACP3 (0.46) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL3079112 | 0.84 | ACP3 (0.46) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL4785593 | 0.84 | TSHR (0.52) | TSHRPOLBALDH1A1HPGDMEN1 | |
| SCHEMBL167715 | 0.84 | AOC3 (0.55) | TSHRPOLBALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129479-A1 | Modified copolymers from ethylen and at least one alpha-olefin and process for its preparation | Société Chimique des Charbonnages S.A. (FR) | 1984-12-27 | — | — | EP | claimed |
| EP-0273274-A2 | Degradation of polyethylene by means of agents generating free radicals | Elf Atochem Deutschland GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |
| EP-0129479-A1 | Modified copolymers from ethylen and at least one alpha-olefin and process for its preparation | Société Chimique des Charbonnages S.A. (FR) | 1984-12-27 | — | — | EP | disclosed |
| US-4027080-A | Crosslinking of polyolefines | PEROXID-CHEMIE GMBH (DT) | 1977-05-31 | — | — | US | disclosed |