Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL9581085 | 0.97 | TSHR (0.55) | AOC3TSHRPOLBLMNAPKM | |
| Ammonia Solution, Strong SCHEMBL4461727 | 0.97 | AOC3 (0.53) | AOC3TSHRPOLBLMNAPKM | |
| SCHEMBL6548106 | 0.91 | CALM1 (0.52) | AOC3TSHRPOLBLMNAPKM | |
| Phenol SCHEMBL28856311 | 0.89 | OPRK1 (0.57) | AOC3TSHRLMNAPKMCYP1A2 | |
| SCHEMBL24141070 | 0.86 | MMP12 (0.53) | AOC3ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL8080450 | 0.86 | HTT (0.41) | AOC3TSHRHTTSMN1; SMN2OPRK1 | |
| SCHEMBL108633 | 0.85 | LMNA (0.54) | AOC3LMNAPKMHPGD | |
| SCHEMBL4785593 | 0.84 | TSHR (0.52) | TSHRPOLBALDH1A1HPGDCYP1A2 | |
| SCHEMBL10697566 | 0.84 | TSHR (0.52) | TSHRPOLBALDH1A1HPGDCYP1A2 | |
| SCHEMBL105419 | 0.83 | LMNA (0.53) | AOC3LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116218615-A | Cleaning compositions and methods of use thereof | 富士胶片电子材料美国有限公司 | 2023-06-06 | — | — | CN | claimed |
| EP-2951179-B1 | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | MERCK PATENT GMBH (DE) | 2020-03-11 | — | — | EP | claimed |
| CN-109574972-A | A kind of 3- alkyl substitution -4- chromanone compound and preparation method thereof | 郑州大学 | 2019-04-05 | — | — | CN | claimed |
| CN-108727904-A | Quantum dot ink | TCL集团股份有限公司 | 2018-11-02 | — | — | CN | claimed |
| CN-104788634-B | A kind of preparation method of drilling fluid high temperature resistance modification sulphonation phenolic resin | 天津中油渤星工程科技有限公司 | 2017-11-07 | — | — | CN | claimed |
| CN-106983671-A | Sunscreen agents containing titanium dioxide | 拜尔斯道夫股份有限公司 | 2017-07-28 | — | — | CN | claimed |
| US-9708321-B2 | Spiro-quinazolinone derivatives and their use as positive allosteric modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2017-07-18 | — | — | US | claimed |
| US-20150361079-A1 | Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | MERCK PATENT GMBH (DE) | 2015-12-17 | — | — | US | claimed |
| EP-2951179-A1 | SPIRO-QUINAZOLINONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND CONDITIONS | Merck Patent GmbH (DE) | 2015-12-09 | — | — | EP | claimed |
| US-20150276568-A1 | MICRO-SCALE LIQUID-LIQUID-LIQUID EXTRACTION | UNIVERSITY OF OSLO (NO) | 2015-10-01 | — | — | US | claimed |
| US-5276008-A | Herbicides and plant growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | claimed |
| WO-1992020663-A1 | SUBSTITUTED TRIAZOLINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | claimed |
| EP-0502307-A2 | Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones | BAYER AG (DE) | 1992-09-09 | — | — | EP | claimed |
| EP-0192492-B1 | PEPTIDES CONTAINING AN ALIPHATIC-AROMATIC KETONE SIDE CHAIN | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1992-01-02 | — | — | EP | claimed |
| US-5073655-A | Alkylation of aromatic hydrocarbon with aromatic alklating hal ide, alcohol or olefin, a mixed oxide of silica or germania wi th alumina, boria, iron oxide or gallium oxide | MOBIL OIL CORP. (US) | 1991-12-17 | — | — | US | claimed |
| CN-85106701-A | 2-substituting group-trimethylene diphosphonate derivatives and the preparation method who contains the formula of medicine of this derivative | — | 1987-03-25 | — | — | CN | claimed |
| US-4518764-A | POLYDIALLYL TEREPHTHALATE ENDCAPPED WITH ALKLARYL HYDROCARBON | OSAKA SODA CO. LTD. (JP) | 1985-05-21 | — | — | US | claimed |
| US-4383705-A | Pressure-sensitive recording material | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-05-17 | — | — | US | claimed |
| EP-0002792-A1 | 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1979-07-11 | — | — | EP | claimed |
| US-4101579-A | Phenethanolamine ethers | ALLEN & HANBURYS LIMITED (GB) | 1978-07-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361079-A1 | Spiro-Quinazolinone Derivatives and their Use as Positive Allosteric Modulators of mGluR4 | GRM4, GRIA4, GRIK4 | AOC3 4707/4885TSHR 839/4885POLB 4700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.