SCHEMBL919366

SCHEMBL919366

[CH2]C(C)CCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
POLB P06746 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
OPRK1 P41145 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23531244 1.00 TSHR (0.48) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL10829234 0.87 MMP12 (0.50) ALDH1A1CYP1A2
SCHEMBL920968 0.86 SIGMAR1 (0.47) MEN1KMT2A
SCHEMBL10697566 0.85 TSHR (0.52) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL21625271 0.85 SIGMAR1 (0.49)
SCHEMBL4785593 0.80 TSHR (0.52) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL167715 0.80 AOC3 (0.55) TSHRPOLBMEN1KMT2AALDH1A1
SCHEMBL7441548 0.80 ALDH1A1 (0.48) TSHRALDH1A1HPGDSMN1; SMN2ALOX15
Ammonia Solution, Strong SCHEMBL4461727 0.78 AOC3 (0.53) TSHRPOLBMEN1KMT2AALDH1A1
Hydrogen Peroxide SCHEMBL9581085 0.78 TSHR (0.55) TSHRPOLBMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108690217-B Carbon fiber recycling composition and method 波音公司 2022-07-15 CN claimed
US-11377535-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2022-07-05 US claimed
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 US claimed
US-10611892-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2020-04-07 US claimed
US-20180291174-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2018-10-11 US claimed
US-7402576-B2 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2008-07-22 US claimed
EP-1599487-B1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2007-07-11 EP claimed
US-20060052616-A1 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2006-03-09 US claimed
CN-1705674-A phosphinic acid analogs of glutamic acid GIVAUDAN SA (CH) 2005-12-07 CN claimed
WO-2004048394-A1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2004-06-10 WO claimed
US-20240148727-A1 OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2024-05-09 US disclosed
US-11911381-B2 Optically active azabicyclo ring derivative Sumitomo Pharma Co., Ltd. (JP) 2024-02-27 US disclosed
CN-112771055-B Optically active bridged piperidine derivatives 住友制药株式会社 2023-10-20 CN disclosed
CN-112585140-B Optically active azabicyclo derivatives 住友制药株式会社 2023-07-04 CN disclosed
CN-108690217-B Carbon fiber recycling composition and method 波音公司 2022-07-15 CN disclosed
CN-1049664-A Optically active 4-hydroxyl-8-(3-low-alkoxy-4-phenyl sulfinyl phenyl) pyrazolo [1,5-α]-1,3,5-triazines salt and method for making thereof OTSUKA PHARMA CO LTD (JP) 1991-03-06 CN disclosed
US-4302588-A 5-(3-SUBSTITUTED AMINO)-2-HYDROXY-PROPYLOXY)-8-HYDROXY OR ALKOXY-CARBOSTYRILS, ADRENERGIC BLOCKING AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-11-24 US disclosed
US-4289883-A ADRENERGIC BLOCKING AGENTS OF EXCELLENT CARDIOSELECTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1981-09-15 US disclosed
US-4210753-A TREATMENT OF CARDIAC DISORDERS AND CHRONIC LUNG DISEASE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1980-07-01 US disclosed
US-4147869-A ADRENERGIC BLOCKING AGENTS FOR TREATMENT OF ANGINA PECTORIS, ARRHYTHMIA AND HYPERTENSION OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1979-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052616-A1 Phosphinic acid analogs of glutamate GLUL, GRIA1, GRM1 TSHR 2006/4885POLB 3981/4885MEN1 1644/4885
US-11911381-B2 Optically active azabicyclo ring derivative MLLT3, MEN1, MLLT1 TSHR 3525/4885POLB 4302/4885MEN1 2/4885
US-20240148727-A1 OPTICALLY ACTIVE AZABICYCLO RING DERIVATIVE MLLT3, MEN1, MLLT1 TSHR 3525/4885POLB 4302/4885MEN1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.