Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 3/20 | 0.41 |
| ▸ | GSR | P00390 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1917380 | 0.82 | PIN1 (0.41) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL10697769 | 0.77 | TDP1 (0.38) | ALDH1A1KMT2ATXNRD1MEN1TDP1 | |
| SCHEMBL30791429 | 0.77 | PTGS1 (0.47) | MAPTMERTKHTTALDH1A1KMT2A | |
| SCHEMBL31063282 | 0.77 | MAPT (0.38) | MAPTMERTKHTTALDH1A1KMT2A | |
| SCHEMBL963587 | 0.76 | TXNRD1 (0.47) | MAPTMERTKHTTALDH1A1TXNRD1 | |
| SCHEMBL937505 | 0.75 | MERTK (0.49) | MAPTMERTKHTTTXNRD1GSR | |
| SCHEMBL29990867 | 0.75 | MERTK (0.49) | MAPTMERTKHTTTXNRD1GSR | |
| SCHEMBL6642983 | 0.75 | ALDH1A1 (0.48) | MAPTMERTKHTTALDH1A1KMT2A | |
| SCHEMBL6646943 | 0.75 | MAPT (0.45) | MAPTMERTKHTTALDH1A1KMT2A | |
| SCHEMBL30889027 | 0.75 | ALDH1A1 (0.48) | MAPTMERTKHTTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |