Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063291 | 0.82 | P2RX3 (0.36) | MAPK1LMNAL3MBTL1HTTKMT2A | |
| SCHEMBL29241492 | 0.80 | MAPT (0.46) | MAPTMAPK1LMNAL3MBTL1MEN1 | |
| SCHEMBL3768551 | 0.80 | MAPT (0.42) | MAPTLMNAL3MBTL1HTTKMT2A | |
| SCHEMBL1736929 | 0.79 | NR1D1 (0.43) | MAPTLMNAL3MBTL1HTTMEN1 | |
| SCHEMBL10697671 | 0.77 | MAPT (0.44) | MAPTTHRBLMNAL3MBTL1HTT | |
| SCHEMBL2322127 | 0.74 | KMT2A (0.45) | MAPTTHRBMAPK1LMNAL3MBTL1 | |
| SCHEMBL9710379 | 0.74 | MAPT (0.40) | MAPTMAPK1LMNAL3MBTL1MEN1 | |
| SCHEMBL3961361 | 0.73 | KMT2A (0.44) | MAPTTHRBMAPK1LMNAL3MBTL1 | |
| SCHEMBL6646943 | 0.73 | MAPT (0.45) | MAPTMAPK1LMNAL3MBTL1HTT | |
| SCHEMBL23013993 | 0.72 | NR1D1 (0.35) | MAPTTHRBMAPK1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665339-A1 | INHIBITING ALPHA V BETA 8 INTEGRIN | Morphic Therapeutic, Inc. (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173570-A1 | INHIBITING αvβ8 INTEGRIN | MORPHIC THERAPEUTIC, INC. (US) | 2024-08-22 | — | — | WO | disclosed |