Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699606 | 0.87 | TNKS2 (0.43) | KMT2AMEN1GAABRD4CACNA1S | |
| SCHEMBL10698630 | 0.87 | KMT2A (0.37) | KMT2AMEN1GAAARIDE | |
| SCHEMBL10698144 | 0.87 | KDM4E (0.39) | BRD4CCL2 | |
| SCHEMBL10698690 | 0.84 | MEN1 (0.33) | KMT2AMEN1GAACAPN1 | |
| SCHEMBL10696186 | 0.84 | KMT2A (0.43) | KMT2AMEN1GAAARIDE | |
| SCHEMBL10701683 | 0.81 | KDM4E (0.40) | KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10700930 | 0.77 | ALDH1A1 (0.34) | KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL10700358 | 0.76 | TNKS2 (0.43) | KMT2AMEN1GAABRD4CCL2 | |
| SCHEMBL10699106 | 0.75 | ALDH1A1 (0.40) | KMT2AGAABRD4CCL2 | |
| SCHEMBL10700676 | 0.74 | ALDH1A1 (0.38) | KMT2AGAABRD4CCL2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |