Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700985 | 0.90 | KMT2A (0.36) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10697977 | 0.89 | MEN1 (0.36) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10698445 | 0.89 | MEN1 (0.36) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10699480 | 0.88 | KDM4E (0.34) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10694978 | 0.85 | MEN1 (0.36) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10697745 | 0.84 | KMT2A (0.39) | MEN1KMT2ACAPN1GAA | |
| SCHEMBL10699909 | 0.83 | KDM4E (0.38) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10700743 | 0.78 | MEN1 (0.33) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL10700950 | 0.78 | MEN1 (0.36) | MEN1KMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL10699882 | 0.77 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |