Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701042 | 0.80 | OGT (0.36) | LMNA | |
| SCHEMBL10699983 | 0.80 | OPRL1 (0.45) | MAOBDRD4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10700412 | 0.79 | PLG (0.34) | MAOBMAPTLMNAPOLBUSP2 | |
| SCHEMBL10697516 | 0.78 | — | — | |
| SCHEMBL10713607 | 0.72 | GFER (0.39) | DRD4NTSR1NPSR1DRD2 | |
| SCHEMBL10701918 | 0.70 | AMY1A (0.36) | HCRTR1HCRTR2MAPTLMNAPOLB | |
| SCHEMBL10702652 | 0.69 | OGT (0.37) | MAPTLMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL10700416 | 0.69 | AMY1A (0.31) | — | |
| SCHEMBL10698492 | 0.68 | LMNA (0.36) | MAOBMAPTLMNAPOLBUSP2 | |
| SCHEMBL10713096 | 0.68 | GFER (0.41) | DRD4NTSR1LMNAUSP2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0270964-A2 | Process for obtaining substituted fluorobenzenes | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |