⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701042 | 0.86 | OGT (0.36) | — | |
| SCHEMBL10700412 | 0.81 | PLG (0.34) | — | |
| SCHEMBL10700416 | 0.79 | AMY1A (0.31) | — | |
| SCHEMBL10701638 | 0.78 | MAOB (0.32) | — | |
| SCHEMBL10699725 | 0.78 | ATP4A (0.33) | — | |
| SCHEMBL10702652 | 0.78 | OGT (0.37) | — | |
| SCHEMBL10697900 | 0.78 | MAOB (0.38) | — | |
| SCHEMBL10700992 | 0.77 | PTGS2 (0.42) | — | |
| SCHEMBL10701918 | 0.75 | AMY1A (0.36) | — | |
| SCHEMBL10700413 | 0.74 | OGT (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0280128-A2 | Process for the preparation of 1-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranoxyl) pyrimidines, and intermediates | BAYER AG (DE) | 1988-08-31 | — | — | EP | disclosed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |