Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | OGT | O15294 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10701042 | 0.91 | OGT (0.36) | PLGPLAUF10F2PLAT | |
| SCHEMBL10698492 | 0.85 | LMNA (0.36) | PLGPLAUF10F2PLAT | |
| SCHEMBL10702722 | 0.81 | ACHE (0.35) | PLGPLAUF10F2PLAT | |
| SCHEMBL10697516 | 0.81 | — | — | |
| SCHEMBL10701918 | 0.81 | AMY1A (0.36) | F10MAPTRAB9ALMNANPC1 | |
| SCHEMBL10697900 | 0.79 | MAOB (0.38) | MAPTLMNASMN1; SMN2TP53KDM4E | |
| SCHEMBL10700237 | 0.78 | PTGS2 (0.47) | MAPTRAB9ALMNANPC1TP53 | |
| SCHEMBL10700413 | 0.78 | OGT (0.36) | PLGPLAUF10OGTMAPT | |
| SCHEMBL10702652 | 0.78 | OGT (0.37) | PLGPLAUF10OGTMAPT | |
| SCHEMBL10702170 | 0.76 | MAPT (0.38) | PLGPLAUF10F2PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | claimed |
| EP-0251536-A1 | Benzimidazoles, their production, formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1988-01-07 | — | — | EP | disclosed |