Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318251 | 0.83 | LMNA (0.65) | LMNAMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL8150113 | 0.81 | HCRTR2 (0.49) | LMNAMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL10700520 | 0.79 | MAPT (0.51) | LMNAMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30961584 | 0.76 | ALDH1A1 (0.59) | ALDH1A1HTR7 | |
| Guaiactamine SCHEMBL25797 | 0.76 | ALDH1A1 (0.78) | LMNASMN1; SMN2ALDH1A1HPGDL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9252419 | 0.75 | LMNA (0.72) | LMNAMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL10696261 | 0.75 | L3MBTL1 (0.53) | LMNAALDH1A1NPC1HPGDHSD17B10 | |
| SCHEMBL7899947 | 0.74 | LMNA (0.72) | LMNAMTNR1AMTNR1BSMN1; SMN2ALDH1A1 | |
| SCHEMBL9301156 | 0.74 | L3MBTL1 (0.65) | LMNASMN1; SMN2ALDH1A1ADRB2HPGD | |
| SCHEMBL15391794 | 0.74 | SMN1; SMN2 (0.70) | LMNAMTNR1AMTNR1BSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |