Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 10/20 | 0.35 |
| ▸ | CTSS | P25774 | 9/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10371265 | 0.79 | NOS1 (0.44) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL10719631 | 0.77 | CTSK (0.42) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL2522650 | 0.74 | KCNH2 (0.67) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL10369437 | 0.74 | CTSK (0.38) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL9706479 | 0.74 | CTSK (0.40) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL10696923 | 0.74 | MEN1 (0.57) | ADORA2AADORA1KDM4E | |
| SCHEMBL10695693 | 0.74 | CCR1 (0.52) | NOS2NOS3ADORA2AADORA1TGFBR1 | |
| SCHEMBL10370101 | 0.73 | NOS1 (0.39) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL10372073 | 0.73 | LMNA (0.47) | KCNH2NOS1NOS2NOS3CTSK | |
| SCHEMBL7685870 | 0.73 | KCNH2 (0.59) | KCNH2NOS1NOS2NOS3CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278610-A2 | Novel pyridinyl-s-triazine derivatives, method for production thereof and a fungicide containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-08-17 | — | — | EP | claimed |