Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.40 |
| ▸ | CTSS | P25774 | 8/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | IDH2 | P48735 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9027527 | 0.85 | ADORA2A (0.40) | CTSKCTSSPOLBCTDSP1L3MBTL1 | |
| SCHEMBL10372073 | 0.84 | LMNA (0.47) | CTSKCTSSNOS3NOS1NOS2 | |
| SCHEMBL10429456 | 0.75 | FFAR1 (0.41) | CTSKCTSSPOLBMAPTKDM4E | |
| SCHEMBL10719631 | 0.75 | CTSK (0.42) | CTSKCTSSNOS3NOS1NOS2 | |
| SCHEMBL10371265 | 0.74 | NOS1 (0.44) | CTSKCTSSNOS3NOS1NOS2 | |
| SCHEMBL10698102 | 0.74 | KCNH2 (0.42) | CTSKCTSSNOS3NOS1NOS2 | |
| SCHEMBL10369437 | 0.73 | CTSK (0.38) | CTSKCTSSNOS3NOS1NOS2 | |
| SCHEMBL7685870 | 0.72 | KCNH2 (0.59) | CTSKCTSSNOS3NOS1NOS2 | |
| SCHEMBL11515837 | 0.72 | POLB (0.53) | CTSKCTSSPOLBCTDSP1L3MBTL1 | |
| SCHEMBL244011 | 0.72 | CCR1 (0.46) | NOS1NOS2L3MBTL1KDM4ETGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992010490-A1 | PYRIDYL-PYRIMIDIN-DERIVATES, PROCESS FOR PRODUCING THE SAME, AGENTS CONTAINING THE SAME AND THEIR USE AS FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |