SCHEMBL106982

SCHEMBL106982

C=C(C)C(=O)OCCc1ccc(O)c(-n2nc3ccc(OC)cc3n2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
LMNA P02545 3/20 0.36
KDM4E B2RXH2 1/20 0.36
TP53 P04637 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAOA P21397 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A3 Q01959 1/20 0.36
IGF1R P08069 1/20 0.34
ALOX15 P16050 1/20 0.34
MET P08581 3/20 0.34
YWHAG P61981 1/20 0.34
APP P05067 1/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384278 1.00 MAPT (0.36) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL14860490 0.90 MAPT (0.36) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL30039355 0.89 LMNA (0.36) MAPTNPC1RAB9ALMNAKDM4E
SCHEMBL7268063 0.88 NPC1 (0.46) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL93485 0.87 NPC1 (0.47) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL29358846 0.87 NPC1 (0.47) MAPTNPC1RAB9ASMN1; SMN2LMNA
SCHEMBL29384829 0.87 LMNA (0.35) MAPTNPC1RAB9ALMNAKDM4E
SCHEMBL105442 0.87 LMNA (0.35) MAPTNPC1RAB9ALMNAKDM4E
SCHEMBL25407007 0.86 MET (0.41) MAPTNPC1RAB9ASMN1; SMN2MET
SCHEMBL8823408 0.86 LMNA (0.43) MAPTNPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3173826-B1 HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION PEGAVISION CORP (TW) 2019-02-13 EP claimed
EP-3173826-A1 HYDROGEL COMPOSITION AND HYDROGEL CONTACT LENSES MADE OF THE COMPOSITION Pegavision Corporation (TW) 2017-05-31 EP claimed
US-9482788-B2 UV-blocking silicone hydrogel composition and silicone hydrogel contact lens containing thereof PEGAVISION CORPORATION (TW) 2016-11-01 US claimed
US-20160161638-A1 UV-BLOCKING SILICONE HYDROGEL COMPOSITION AND SILICONE HYDROGEL CONTACT LENS CONTAINING THEREOF PEGAVISION CORPORATION (TW) 2016-06-09 US claimed
EP-3029081-A1 Uv-blocking silicone hydrogel composition and silicone hydrogel contact lens containing thereof Pegavision Corporation (TW) 2016-06-08 EP claimed
US-12479194-B2 Laminate TOYOBO CO., LTD. (JP) 2025-11-25 US disclosed
EP-4651688-A1 DEVICE AND METHOD FOR MANUFACTURING DEVICE Toyobo Co., Ltd. (JP) 2025-11-19 EP disclosed
WO-2025089524-A1 BLUE LIGHT SHIELDING FILM AND ELECTRONIC DEVICE COMPRISING SAME 도레이첨단소재 주식회사 2025-05-01 WO disclosed
WO-2024181338-A1 COMPOSITION CONTAINING CARBON MATERIAL 株式会社日本触媒 2024-09-06 WO disclosed
WO-2024150811-A1 DEVICE AND METHOD FOR MANUFACTURING DEVICE 東洋紡株式会社 2024-07-18 WO disclosed
CN-116075368-B Resin composition, cured product, method for producing same, and laminate 三菱化学株式会社 2024-06-11 CN disclosed
CN-118119507-A Laminate of inorganic substrate with protective film and heat-resistant polymer film 东洋纺株式会社 2024-05-31 CN disclosed
US-20020045702-A1 (Meth)acrylate ester-based resin composition NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-18 US disclosed
US-6372355-B1 MINIMIZED COLORING OR DETERIORATION INDUCED BY ULTRAVIOLET RADIATION, WITH INTERLAYER ADHESION AND ABRASION RESISTANCE AND WEATHERABILITY NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-16 US disclosed
US-20020040094-A1 Resin composition for coating and coating composition for curing NIPPON SHOKUBAI CO., LTD. (JP) 2002-04-04 US disclosed
EP-1178080-A2 Curable resin coating composition Nippon Shokubai Co., Ltd. (JP) 2002-02-06 EP disclosed
US-6312802-B1 ADDITION POLYMERS OF 2,2,6,6-TETRAMETHYL-4-PIPERAZINYL ACRYLATES OR ACRYLAMIDES; ADDITION POLYMERS OF (BENZOTRIAZOL-2'-YL)HYDROXYPHENYL ACRYLATES NIPPON SHOKUBAI CO., LTD. (JP) 2001-11-06 US disclosed
US-6200686-B1 CURABLE MIXTURE OF A DICYCLOPENTENYL GROUP-CONTAINING UNSATURATED POLYESTER, UNSATURATED MONOMERS OF AN AROMATIC HYDROCARBON AND AN ALIPHATIC COMPOUND AND A SOLUBLE THERMO-PLASTIC POLYMER; LAMINATED OR JOINT MONOLITHIC MOLDING NIPPON SHOKUBAI CO., LTD. (JP) 2001-03-13 US disclosed
EP-1067223-A1 Polymers for imparting light resistance to fibers, highly light-resistant fibers, and process for producing the fibers NIPPON SHOKUBAI CO., LTD. (JP) 2001-01-10 EP disclosed
EP-1036834-A1 ULTRAVIOLET-ABSORBING LAMINATED RESINOUS MATERIAL Nippon Shokubai Co., Ltd. (JP) 2000-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045702-A1 (Meth)acrylate ester-based resin composition MNAT1, MAT1A, COPE MAPT 24/4885NPC1 4847/4885RAB9A 1744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.