Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 3/20 | 0.55 |
| ▸ | KCNAB1 | Q14722 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.48 |
| ▸ | CA2 | P00918 | 6/20 | 0.48 |
| ▸ | CA9 | Q16790 | 6/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8878995 | 0.84 | KCNA1 (0.65) | KCNA1KCNAB1CA12CA1CA2 | |
| Sulofenur SCHEMBL4174 | 0.84 | KCNA1 (0.65) | KCNA1KCNAB1CA12CA1CA2 | |
| Sulofenur SCHEMBL29359159 | 0.84 | KCNA1 (0.65) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL9486495 | 0.81 | CA12 (0.66) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL10700918 | 0.80 | KCNA1 (0.52) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8877626 | 0.80 | PKM (0.70) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL9487105 | 0.79 | MEN1 (0.62) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL7983217 | 0.78 | KCNA1 (0.53) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL7983130 | 0.78 | KCNA1 (0.50) | KCNA1KCNAB1CA12CA1CA2 | |
| SCHEMBL8646490 | 0.78 | KCNA1 (0.53) | KCNA1KCNAB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291269-A2 | Anti-tumour sulfonyl urea derivatives | ELI LILLY AND COMPANY (US) | 1988-11-17 | — | — | EP | claimed |
| EP-0291269-A2 | Anti-tumour sulfonyl urea derivatives | ELI LILLY AND COMPANY (US) | 1988-11-17 | — | — | EP | disclosed |