SCHEMBL10698364

SCHEMBL10698364

c1ccc(C(/N=N/c2cccnn2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10698367 1.00 MAOA (0.32) MAOAMAOBALDH1A1TSHRKMT2A
SCHEMBL27983624 0.76 GOT1 (0.41) MAOAMAOB
SCHEMBL9700533 0.74 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL9700504 0.74 ALDH1A1 (0.38) ALDH1A1TSHR
SCHEMBL491314 0.68 ALDH1A1 (0.52) MAOAMAOBALDH1A1TSHRKMT2A
SCHEMBL491313 0.68 ALDH1A1 (0.52) MAOAMAOBALDH1A1TSHRKMT2A
SCHEMBL1853792 0.67 MAOA (0.41) MAOAMAOBALDH1A1
SCHEMBL1785971 0.67 GOT1 (0.41)
SCHEMBL1855092 0.63
SCHEMBL3681505 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274409-A2 Process for preparing alkoxyalkyl-idenehydrazinopyridazine derivatives I.S.F. Socièta per Azioni (IT) 1988-07-13 EP disclosed