Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700504 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2RECQLGAATSHR | |
| SCHEMBL10698367 | 0.74 | MAOA (0.32) | ALDH1A1TSHR | |
| SCHEMBL10698364 | 0.74 | MAOA (0.32) | ALDH1A1TSHR | |
| SCHEMBL9700540 | 0.67 | ACSS2 (0.36) | TSHR | |
| SCHEMBL491314 | 0.66 | ALDH1A1 (0.52) | ALDH1A1TSHR | |
| SCHEMBL491313 | 0.66 | ALDH1A1 (0.52) | ALDH1A1TSHR | |
| SCHEMBL15360120 | 0.62 | — | — | |
| SCHEMBL29367162 | 0.62 | — | — | |
| SCHEMBL11293443 | 0.59 | MEN1 (0.59) | ALDH1A1RECQLGAA | |
| SCHEMBL11293444 | 0.59 | MEN1 (0.59) | ALDH1A1RECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274409-A2 | Process for preparing alkoxyalkyl-idenehydrazinopyridazine derivatives | I.S.F. Socièta per Azioni (IT) | 1988-07-13 | — | — | EP | claimed |
| US-5082939-A | Pyridazine derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1992-01-21 | — | — | US | disclosed |
| US-4873328-A | Process for preparing alkoxyalkylidenehydrazinopyridazine derivatives | I.S.F. SOCIETA PER AZIONI (IT) | 1989-10-10 | — | — | US | disclosed |
| EP-0274409-A2 | Process for preparing alkoxyalkyl-idenehydrazinopyridazine derivatives | I.S.F. Socièta per Azioni (IT) | 1988-07-13 | — | — | EP | disclosed |
| US-4632982-A | Triphenylmethyl azo and hydrazino substituted pyridazines | I.S.F. S.P.A. (IT) | 1986-12-30 | — | — | US | disclosed |
| US-4575552-A | Process of making ethyl[6-[ethyl-(2-hydroxypropyl)amino]-3-pyridazinyl]hydrazine carboxylate | I.S.F. S.P.A. (IT) | 1986-03-11 | — | — | US | disclosed |
| EP-0124058-A1 | Preparation of a pharmaceutically active pyridazine derivative | I.S.F. Socièta per Azioni (IT) | 1984-11-07 | — | — | EP | disclosed |