SCHEMBL9862043

SCHEMBL9862043

CCOC(=O)OOC(=O)C=COOC(C)(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
POLB P06746 1/20 0.36
MAPT P10636 7/20 0.34
ALDH1A1 P00352 5/20 0.34
ALOX15 P16050 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 3/20 0.33
MDM2 Q00987 2/20 0.33
HSD11B1 P28845 1/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
PIN1 Q13526 1/20 0.33
MDM4 O15151 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862015 0.87 HCAR2 (0.35) MAPK1MEN1KMT2APOLBMAPT
SCHEMBL9851460 0.86 LMNA (0.37) MAPK1MEN1KMT2AALDH1A1ALOX15
SCHEMBL10482058 0.84 MAPK1 (0.34) MAPK1ALDH1A1ALOX15
SCHEMBL28678971 0.81 MAPK1 (0.52) MAPK1MEN1KMT2APOLBALDH1A1
SCHEMBL5597025 0.80 ALDH1A1 (0.38) ALDH1A1
SCHEMBL9242885 0.79 MAPK1 (0.43) MAPK1KMT2AMAPTALDH1A1ALOX15
SCHEMBL2772376 0.79 MAPK1 (0.43) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL28678972 0.78 MAPK1 (0.48) MAPK1MEN1KMT2APOLBALDH1A1
SCHEMBL10435073 0.78 MAPK1 (0.42) MAPK1MEN1KMT2AALDH1A1ALOX15
SCHEMBL9862034 0.77 MAPK1 (0.41) MAPK1MEN1KMT2APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0423767-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1991-04-24 EP disclosed