Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9862022 | 0.87 | LMNA (0.34) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9862043 | 0.87 | MAPK1 (0.39) | MAPK1MAPTLMNAMDM2POLB | |
| SCHEMBL2772376 | 0.84 | MAPK1 (0.43) | HCAR2MAPK1MAPTAKR1B10AKR1B1 | |
| SCHEMBL10498335 | 0.82 | HCAR2 (0.33) | HCAR2ALDH1A1 | |
| SCHEMBL10435073 | 0.81 | MAPK1 (0.42) | HCAR2MAPK1AKR1B10AKR1B1LMNA | |
| SCHEMBL9862102 | 0.80 | HCAR2 (0.32) | HCAR2ALDH1A1 | |
| SCHEMBL28678971 | 0.79 | MAPK1 (0.52) | MAPK1POLBALDH1A1CHRM2CHRM4 | |
| SCHEMBL8525638 | 0.78 | HCAR2 (0.37) | HCAR2MAPK1MAPTAKR1B10AKR1B1 | |
| SCHEMBL9242885 | 0.77 | MAPK1 (0.43) | HCAR2MAPK1MAPTAKR1B10AKR1B1 | |
| SCHEMBL7692322 | 0.76 | HCAR2 (0.35) | HCAR2MAPK1MAPTAKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423767-A2 | Thermoplastic resin composition and method for preparing the same | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1991-04-24 | — | — | EP | disclosed |