Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697977 | 0.90 | MEN1 (0.36) | MEN1KMT2ABRD4CCL2ALDH1A1 | |
| SCHEMBL10698445 | 0.90 | MEN1 (0.36) | MEN1KMT2ACACNA1SBRD4ALDH1A1 | |
| SCHEMBL10699882 | 0.89 | KDM4E (0.35) | BRD4CCL2ALDH1A1KDM4EHPGD | |
| SCHEMBL10700358 | 0.85 | TNKS2 (0.43) | MEN1KMT2ACACNA1SBRD4CCL2 | |
| SCHEMBL10700488 | 0.80 | BMPR1B (0.37) | MEN1KMT2AALDH1A1KDM4EABCB1 | |
| SCHEMBL10699610 | 0.80 | MEN1 (0.36) | MEN1KMT2AALDH1A1KDM4EABCB1 | |
| SCHEMBL10698552 | 0.79 | PDE6D (0.36) | MEN1KMT2ABRD4CCL2ALDH1A1 | |
| SCHEMBL10698690 | 0.78 | MEN1 (0.33) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL10699480 | 0.77 | KDM4E (0.34) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| SCHEMBL10700985 | 0.77 | KMT2A (0.36) | MEN1KMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |